Tuberculosis (TB) is a life threatening contagious disease caused by the bacteria
M. tuberculosis that primarily affects lungs. Other mycobacteria from the
M. tuberculosis complex such as
M. bovis,
M. africanum,
M. canetti and
M. microti, can also cause tuberculosis, but these species do not usually infect healthy adults. Approximately, one third of the world's population is infected with
M. tuberculosis. Every year, about 8 million new cases are reported and 3 million deaths occur due to this dreaded infection. If left untreated, this disease can be fatal. For this reason, accurate and early diagnosis of tuberculosis is important for effective management of the disease.
Spoligotyping (Spacer oligonucleotide typing) is a novel method that can be simultaneously used for detection as well as typing of the
M. tuberculosis complex. This is a PCR-based method, which depends on the amplification of of a highly polymorphic direct repeat (DR) locus in
M. tuberculosis genome.
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About Ocimum
Ocimum Biosolutions is a global life sciences R&D enabling company with three focus areas, BioIT, BioMolecules, and BioResearch. Ocimum delivers end to end genomic products and services out of three strategic locations worldwide, Gaithersburg MD, Indianapolis IN (United States), IJsselstien (The Netherlands), Hyderabad (India).
The BioIT Division consists of reference databases like The BioExpress® and The ToxExpress® System, Enterprise software solutions like Genesis, web based solutions like ASCENTA® and SCIANTIS® . It also includes three 21 CFR Part 11 & GLP compliant, Lab Information Management Systems (LIMS) products - Biotracker™, Pharmatracker™ and Toxchek™ and a suite of bioinformatics products, Genchek™ (sequence analysis), OptGene™ (gene design), Genowiz™ (microarray data analysis) and iRNAchek™ (iRNA template design). The division also offers specialized data analysis for different kinds of "omics" data and other custom software services.
The BioResearch Division provides GLP compliant gene expression data generation services. The division provides valuable expertise and services experience in toxicogenomics, biomarkers clinical genomics and consumer genomics area. more...
The BioMolecules Division produces microarrays and oligonucleotides.